I don't see why you wouldn't be able to put the non run flats on the same rims and the TPMS should be fine as long as you don't change rims. The ride is probably a bit more harsh with the run flats due to the stiff sidewall design but I doubt there's any real difference in performance and handling.

I recently hit a pothole and the run flats got me home safe and without a hassle. I would choose the run flats over non any day.

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2022 X5M Comp Dravit Grey/Full Silverstone
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2018 M5 Black/Full Silverstone
2015 X5M Donington Grey/Full Silverstone
2010 X5M Space Grey/Full Silverstone
2003 4.6is Silver/Black