No, it doesn't interfere with it at all. I don't tend to have the sunroof open when it is installed, as there is more wind noise, but I could do so.

I like having the ability to monitor the bikes through the moonroof while driving. I can see if they are moving around or not.

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2007 X3 3.0si, 6 MT, Premium, White

Retired:
2008 535i, 6 MT, M Sport, Premium, Space Grey
2003 X5 3.0 Steptronic, Premium, Titanium Silver
2002 325xi 5 MT, Steel Grey
2004 Z4 3.0 Premium, Sport, SMG, Maldives Blue