Update on this:

Misfires returned after the adaptations reset...

Replaced fuel pump, fuel filter, and regulator. No change.
Replaced CCV valve. No change.
New plugs, coils. No change.
New O2 sensors. No change.
Removed OEtune flash (simply to rule it out). No change. (Actually misfires more now!).
New DISA. No change.
Replaced throttle body. No change.
Smoke tested three times. No leaks. No change.

WTF!! About ready to drive this truck into a pond/lake!!

Still only P0300 - P0306 codes begin thrown...

(Oil consumption has dissipated since CCV replacement. Was only 20K miles on the replaced CCV)