My X5 doesn't have dsp so I didn't research into it much but this is from Seicane's site.
Quote:
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If your X5 E53 is also with DSP, this unit also can fit.Notice:It only supports BMW X5 DSP from year 2002 to 2007. BMW X5 DSP from year 2000 to 2001 will not work after installing this unit.
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I have no idea what you can or can't remove with the dsp setup.
I am still using the factory amp in mine with the radio and nav module removed along with the cd changer.