No. You would need to have the E53 wheel hub openings bored to 74.1mm. Or, assuming the E53 wheel's offsets support it, a hub-centric wheel spacer with a 74.1mm bore on the back and a 72.6mm hub flange on the front could be used. If you really like the wheels, I'd get them properly bored.

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8/2011 X5 xDrive35d Sport, Black Sapphire Metallic, Black Nevada Leather, Fine Burr Walnut Trim
2/2001 M5, Jet Black, Exclusive Complete Black Walk Nappa Point Heritage Leather, Black Cubic Trim