I don't think so. Although there probably is a quality difference between clips. I think people think the black clips (OEM or aftermarket) are better than the white clips..though I am not sure about this. When the regulators fail there isn't much to be done. Like-wise, some folks prefer OEM or OEM quality regulators other do fine with the cheaper ones.

I think keeping the window guides lubricated with silicone spray and not using the windows in freezing temps (prob not your issue) can go a long way toward keeping them working. Don't let anybody hang on a window either.