With a urethane bushing in comparison to a rubber bushing--yes--set it and forget it. The durometer on a poly bushing will nearly never deform. Therefore, the adjustment of the bushing itself will most likely never need to be re-adjusted. Things like ball joints, control arms, etc, will need adjustment as those parts wear over time due to metal-on-metal contact.

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2003 BMW X5 3.0i -- MT5, 3.64s final gears, H&R lowering springs, K-Mac bushing kit
2007 BMW X3 3.0Si -- MT6