I have been chasing a wind noise on my 4.6 for a decade.
Turned out the foam insulation was not adhered well.
The foam sheet was fair. I replaced both drivers door and passenger left
side rear. I used a hair dryer and got it softened and squish able.
Test drive at 80MPH the wind noise is minimal.

I didn't think a poor seal job on the foam panel would be a problem.
For those with a wind noise of undetermined location. Start with the
Door panel.

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2003 4.6is X5
2003 525it
2003 E53 X5 Standard shift