I have a 55lb Pit Bull (which is much smaller size wise then a full grown lab) but I have taken her on trips from Maryland to Vermont with me. She simply lays on the back seat. However, while a pup, best bet is to put the dog in the far back area. Make sure you keep the rules clear that the dog is not allowed to jump all over the leather (as the claws can make nice rips).

As with most things, 'parental' direction is key.

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We the People of the United States, in Order to form a more perfect Union, establish Justice, insure domestic Tranquility, provide for the common defence, promote the general Welfare, and secure the Blessings of Liberty to ourselves and our Posterity, do ordain and establish this Constitution for the United States of America.