It sound like one of the 12-pin plugs into the radio module has come out. Give the radio a check to confirm that all of its plugs are solidly connected.

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2000 E38 750iL Highline Edition, Upgraded with the lastest 2006 X5 Electronics
MKIV Navigation, 16:9 Display, Bluetooth, TV/Video with Backup Camera, Sirius, and Aux Input