My townhouse has audio wiring to every room in the house for recessed speakers, but I haven't installed the speakers in the ceilings of the 2nd and 3rd floors yet. It's also wired for remote control infra red relay so i can be in the loft on the 3rd floor and point the remote at the relay panel on the wall (every room has a relay panel by the light switch) and it will operate the components in the living room on the 1st floor.
I haven't gone beyond what i've described here so far, I'm still in "holy crap i just bought a newly built brand new house and need furniture, some light fixtures and paint and and and " mode... it's overwhelming some times.