If you never go up to the mountain to ski/snowboard, then the Yoko would be my choice. The Latitudes are still fairly new and there isn't really much user data on them yet (though they are OEM for the new MDX). The tread pattern of the Latitudes look like they can potentially do the same thing as your Toyos, so who knows Have to wait and see what owners are reporting after they logged 20k-25k miles with them. What about the Pirelli Scorpion Zero or even the OEM Michelin Diamaris?

The Big Easy's suggestion of -1.15 is actually very reasonable for your normal driving needs, especially if you have the staggered setup. I currently have -1.90 and needs to constantly keep the tire pressure at 34-36psi in order to maintain even tire wear. If I let it drop below 34psi for any length of time, the inner edge will begin to wear more. I'm considering taking the suggested -1.15 setup as well.