Hmm... not sure on the lodging despite the fact I just returned from that area. We made it a day trip from the SF area (actually, from San Ramon). Wasn't a far drive though.........I dont recall seeing many choices in terms of lodging in Napa. Maybe you could try nearby places like Sonoma. . Traffic is bad on weekends so they say, so I'd recommend a weekday like what I did.

Food is great at the Rutherford Grill off Rt 29 though.