D mode 95% of the time. S mode when I'm feeling like a jerk-but I find the downshifts are a bit harsh. On long highway trips I almost always use manual mode to force the X to keep 6th gear. I think the propensity for the transmission to downshift every time I hit resume on the cruise control is annoying. Sure it gets you there fast-but the X has more than enough torque to go from 80 to 85 without having to downshift.

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06 4.4i
01 330cic