Nope, no pre-wire.

The major differences are:

1. You need to add the set of wires that run from the nav computer in the trunk to the in-dash display that carry the video signals and audio from the tape deck.
2. You need to re-route the radio wiring harness from the dash to the trunk next to the battery.

This was a common post-sale project. BMW used to offer a factory navigation retrofit kit that had a cool adapter harness that routed the radio wiring to the trunk and was bundled with the screen video wiring. That made the installation much easier. However, I do not think that kit is available any longer, and it was expensive compared to buying an original navigation harness.

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2000 E38 750iL Highline Edition, Upgraded with the lastest 2006 X5 Electronics
MKIV Navigation, 16:9 Display, Bluetooth, TV/Video with Backup Camera, Sirius, and Aux Input