BMW already thought about it. It won't work unless you remove all the front drive components to accommodate the oil pan on the S62. In addition, the other reason was there was not an automatic transmission built at the time to harness the power and torque of the S62 so BMW opted to simply increase the stroke of the 4.4 N62.

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2006 4.8iS Black/Black with custom Audison Voce/Image Dynamics sound
Production Date - 10/05