Upstream/downstream lean on all O2 sensors with random misfire

[cmccrac]

Codes are
P 0300
P 0147
P0149
P114D
P2195
P2197

Its a BMW X5 E70 3.0L inline six, n52b30 with 150k on it. 1 year ago I replaced the plugs and air filter oil change with filter. Two weeks ago I had to replace the fuel pump...now this. Tomorrow I can check the fuel pressure at the rail.Could use some advice....is this a bad o2 sensor leaning out banks1 & 2, not communicating with the computer, or good sensors indicating vacuum leak or perhaps poor fuel delivery. Which of the two scenarios is more likely to accompany random misfire? Thanks in advance.