22" tire size advice

[ttzcar]

So I've tried researching this entire forum before posting and could not find an answer.
I saw some rims on Ebay, that I am about ready to order. I have a couple of days to make the decision. They're 22 x 9.5 front and back. I guess they're all the same so I'd be losing my off-set? Is this correct?
Now the true question is with 9.5 wide rims could I fit 285's on there? Because I have 285 x 19's now and anything thinner than that is a no go for me. 22's x 10's are alot more expensive than these 9.5's.
Also, say this works out. Could I fit a 45 series tire on 22's or would it rub somwhere? 285/45/22? A buddy has a 50 series tire on his Escalade and looks looks nice. I'm not a fan of the really thin tire looks, but I guess I'll have to do it if there's not other option.

Thanks,