The good news, after months of searching we just picked up an '08 4.8 to replace my wife's E53 3.0 and wow, wonder why we waited so long.

Thanks to all that have answered my questions while I was shopping.
I'm already comfortable navigating iDrive, it is really intuitive, and we are blown away by the updates to our previous model and the extra power from the V8. I'm wondering if there is something wrong with the remote door control system though, I can't get it to respond at all. I know....RTFM. The manual says to turn the ignition on, hold down the left and right buttons (1 and 3 I assume) under the rear view mirror for 20 sec until the little LED flashes to clear the memory. After numerous attempts, I can't get the LED to flash.
I tried simply coding it to our opener without deleting the memory, and still can't get it to respond or learn the code, and again no flashing LED. Since we are new to comfort access and the "keyless ignition" maybe I'm not actually turning the ignition on?? I am inserting the key and the display comes on, chiming tone, etc, so I think I am.
Any ideas? Anyone have a similar issue?
Hopefully this is simply a newbie issue!
Thanks.